《英文msh詞典》H-ras Oncogene
[入口詞] H-ras Oncogene
[主題詞] Genes,ras
[英文釋義] Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras,Ha-ras,rasH) and Kirsten (K-ras,Ki-ras,rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human,avian,murine,and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.